3e. Frontotemporal Dementia

Frontotemporal dementia (FTD) is caused when nerve cells in the frontal and temporal lobes of the brain break down. We learned in lesson 2 that the frontal lobes are responsible for our movement, planning skills, behavior, and personality. Our temporal lobes are responsible for verbal and non-verbal information, processing emotions, and memory retention.

 

There are many different types of frontotemporal dementias. Let’s review a couple; use the flip cards below to learn more.

Pick's Disease
  • Nerve cells become abnormal and swell up before they die
  • The brain also has abnormal structures called Pick bodies; these are made up of tau proteins
Familial FTD
  • Commonly linked to a genetic mutation 
  • Passed down through family
Primary Progressive Aphasia (PPA)
  • Aphasia refers to a lack of language functions, such as speaking, naming objects, and understanding what someone is saying
  • Begins as a language disorder and may progress to affect memory and attention 
  • Patients with PPA may eventually develop symptoms of dementia

Symptoms of frontotemporal dementia include:

Behavioral & Emotional
  • Impulsive behaviors
  • Extreme expressions of emotion 
  • Trouble planning or organizing
Movement
  • Shaky hands
  • Difficulty balancing or walking
Language
  • Trouble understanding speech
  • Difficulty talking

Patients with FTD live on average 5-10 years after they are diagnosed. They can experience memory loss in later stages of the disease.